Dogs commonly suffer from hemangiosarcoma, with breeds like the golden retriever carrying heritable genetic factors that put them at high risk.  The most common tumor locations are the spleen, right auricle of the heart, liver, and skin or subcutaneous tissue.   

Treatment protocols for dogs with hemangiosarcoma similarly involve wide surgical resection, followed by adjuvant chemotherapy. Survival times varies from 4–6 months after surgical resection with adjuvant chemotherapy.   

Please refer the following research article titled: 

Comparative Genomics Reveals Shared Mutational Landscape in Canine Hemangiosarcoma and Human Angiosarcoma, 


#M. Breen, J.F. Modiano, I. Elvers, and K. Lindblad-Toh contributed equally to this article.

*Corresponding Authors: Kate Megquier, Broad Institute of Harvard and MIT, 415 Main St., 75A-6108B, Cambridge, MA 02142. Phone: 617-714-8919; E-mail:; and Kerstin Lindblad-Toh,

Mol Cancer Res 2019;17:2410–21


"......Biological risk factors have not yet been identified in dogs. Genetically, dog breeds display differential predisposition to specific cancers, indicating that there are heritable risk factors that have become common as a result of inbreeding based on selection or drift. In a previous genome-wide association study, we identified several loci significantly associated with the risk of hemangiosarcoma in the golden retriever......"